Wang MY et al., Morinda citrifolia (Noni): A Literature Review and Recent Advances in Noni Research. Acta Pharmacol Sin. 2002 Dec; 23 (12): 1127-41.
Morinda citrifolia L. (Noni) has been used in folk remedies by Polynesians for over 2000 years, and is reported to have a broad range of therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, antihelmin, analgesic, hypotensive, anti-inflammatory, and immune enhancing effects. Includes data on allergenicity and toxicity, which shows no observed adverse effects (NOAE). Hirazumi A, Furusawa E. An Immunomodulatory Polysaccharide-rich Substance from the Fruit Juice of Morinda citrifolia (noni) with Antitumour Activity. Phytother Res. 1999 Aug; 13(5): 380-7.
The fruit juice of Morinda citrifolia L. (Noni) contains a polysaccharide-rich substance (noni-ppt) with antitumor activity in the Lewis lung carcinoma (LLC) peritoneal cancinomatosis model. The therapeutic administration of noni-ppt significantly enhanced the duration of survival of inbred syngeneic LLC tumor bearing mice, which seems to suggest that noni-ppt may suppress tumor growth through activation of the host immune system and stimulate the release of certain interleukins and nitric oxide (NO).
Gerson, S. Green, L. Preliminary Evaluation of the Antimicrobial Activity of Extracts of Morinda citrifolia L. 2002 General Meeting of American Society for Microbiology. Morinda citrifolia was shown to have antimicrobial and antifungal properties against A. niger, C. albicans, E. coli, S. aureus and T. mentagrophytes.
Opinion of the Scientific Committee on Foods on Tahitian Noni® Juice, European Commission. SCF/CS/NF/DOS/18 ADD 2 Final. 11, December 2002. Sub-chronic and acute oral toxicity studies of Tahitian Noni® Juice measured clinical signs, food consumption, weight gain, hematology, clinical chemistry, selective organ weights, and tissue samples of 55 organs (for histology). The No-Observable-Adverse-Effect-Level (NOAEL) was 80 g/kg which is more than 8% of the animals’ body weight.
B. A. Mueller, et al. Am J Kidney Dis. 2000 Feb; 35(2): 330-2,
They reported that “The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L, similar to that in orange juice and tomato juice… [and] …may be surreptitious source of potassium in patients with renal disease.” Tahitian Noni® Juice is not a significant source of potassium. B. A. Mueller in USA Today, March 28, 2000 retracted his previous conclusion, stating that his analysis was made on a different noni product and not on Tahitian Noni® Juice and the amount of potassium in the brand of noni juice he analyzed in his study was “only 65 milligrams of potassium per 1 ounce serving, as much as you'd get in 2 inches of a banana.”
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